Die Forschung in der Gendermedizin ist von Interdisziplinarität geprägt. UZH Gendermedizin arbeitet mit Forschenden aus den verschiedenen, medizinischen Fachbereichen zusammen, um die geschlechtsspezifischen Aspekte von Gesundheit und Krankheit ganzheitlich zu untersuchen und die Translation zwischen Forschung und Klinik optimal zu gewährleisten.

Unsere Forschungsprojekte im Überblick:

Single-cell biomarker discovery for precision medicine in gender-specific
psoriasis treatment

This study examines gender-specific psorisasis treatments for precision medicine using molecular and celluar techniques. The project aims at improving the lives of patients of all genders.

Kontakt: PD Dr. Julia-Tatjana Maul, Klinik für Dermatologie, UniversitätsSpital Zürich

Are you looking for your master thesis, your research internship, or your medical doctoral thesis in Neuropsychiatry?

Sex- and gender-specific factors in depression (PDF, 45 KB)
Sex- and gender-specific factors become increasingly relevant in brain research and
clinical practice to provide better personalized medicine. Major depressive disorder
(MDD) is a model disease regarding sex- and gender-specific factors in the diagnosis and treatment as current data suggests that women are twice as often affected as men over the adult lifespan. It is currently the matter of debate, whether this imbalance of MDD prevalence between sexes is real or the consequence of underdiagnosed male depression. Therefore, our group will perform a systematic review and meta-analysis to get further insights in this important topic.

Kontakt: Dr. med. Katrin Rauen, FEBN

Zurich Women Cardiovascular Health Initiative

This interdisciplinary project investigates the co-morbidities of ischemic heart disease and brain disease in women. The longitudinal cohort study follows younger women (35-55 year-olds) and includes non-pharmaceutical interventions aimed at the reduction of stress and other risk factors of cardiovascular disease.

Weitere Informationen zur Studie

Kontakt: Prof. Cathérine Gebhard, Center for Molecular Cardiology, Universität Zürich & Prof. Susanne Wegener, Klinik für Neurologie, UniversitätsSpital Zürich

Age-Dependent Remodelling of the Female Heart: Exploring the Role of Endocrine Factors and Sympathetic Modulation

The project assesses the impact of (patho)physiological factors contributing to sex- and age-related differences in cardiac function with a specific emphasis on sex hormones and their receptors, differences in genetic predisposition, neurohumoral signalling, and gender-based lifestyle factors.

Weitere Informationen zur Studie

Kontakt: Prof. Cathérine Gebhard, Center for Molecular Cardiology, Universität Zürich

Gender Differences in Heart-Brain-Crosstalk: Role of Inflammation, Sympathetic Pathways, and Psychosocial Complexity

This research project investigates novel female-specific targets for cardiovascular disease in women by exploring the heart-brain-crosstalk. It is aimed at identifying new risk factors that explain the increasing occurence of cardiovascular disease in women under the age of 55.

Weitere Informationen zur Studie

Kontakt: Prof. Cathérine Gebhard, Center for Molecular Cardiology, Universität Zürich

Sex Differences in the Development and Clinical Course of Left Ventricular Hypertrophy

The study examines the role of cardiac inflammation and sympathetic activity associated with left ventricular hypertrophy in women. The goal is to delineate novel diagnostic and risk assesment strategies for both men and women with left ventricular hypertrophy.

Kontakt:  Dr. Susan Bengs, Center for Molecular Cardiology, Universität Zürich

Impact of Sex and Gender on COVID-19 Outcomes

Mortality in COVID-19 patients is highest in aged men and men with pre-existing cardiovascular diseases. This research analyses available clinical and epidemiological data on ageing, co-morbidities and lifestyle to elucidate the role of sex and gender variables in the COVID-19 disease progression.

Weitere Informationen zur Studie

Kontakt: Prof. Cathérine Gebhard, Center for Molecular Cardiology, Universität Zürich & Dr. Caroline Gebhard, Intensivstation, Universitätsspital Basel

Sex Differences in Myocardial Perfusion: The Role of Sex Hormones

Research has observed a high prevalence of visually non-detectable dysfunction of the coronary microvasculature in female patients. This research uses positron emission tomography to trace perfusion and identify key sex determinants that affect microvascular function.

Kontakt: Dr. Ahmed Haider, Center for Molecular Cardiology, Universität Zürich

Sex Differences in the Communication of Headaches

The study explores how different primary headaches are felt and communicated differently in patients with different sexes. The project is a collaboration with the UZH Linguistics Department.

Weitere Informationen zur Studie

Kontakt: Prof. Susanne Wegener, Klinik für Neurologie, UniversitätsSpital Zürich

Women's Cardiovascular Health

Based on previous Swiss Health Surveys, this research analyzes trends in traditional and non-traditional cardiovascular risk factors in Switzerland with a focus on sex differences. A particular focus is the interplay between heart and brain in patients with stroke.

Weitere Informationen zur Studie

Kontakt: Prof. Susanne Wegener, Klinik für Neurologie, UniversitätsSpital Zürich

Geschlechterunterschiede in der Parodontitis

Ziel der Querschnittsstudie am Zentrum für Zahnmedizin ist es eine Assoziation von Gender mit Parodontitis zu zeigen und damit sowohl das kulturelle als auch das biologische Geschlecht als unabhängige Einflussfaktoren für Parodontitis auszumachen.

Doktorandin: Livia Osterwalder, med. dent.
Kontakt: Prof. Patrick R. Schmidlin, Klinik für Zahnerhaltung und Präventivzahnmedizin, Universität Zürich